10 Best Ergonomic Mouse For Large Hands – [2022 REVIEW]

Are You getting uncomfortable with your mouse and looking for the Best Ergonomic Mouse for Large Hands? This article will cover 10 ergonomic mouse from which you can choose one.

While owning a laptop or a PC with good specifications is an essential part of achieving optimum experience in your daily life. Having a well-designed mouse to operate your devices is equally important to gain that smooth and comfortable experience.

Whether you are a gamer, corporate professional, or even a casual user who uses pc or laptop for productive purposes, using a mouse that is comfortable for your hands will increase your experience many times over.

Although there is a wide range of options in terms of designs and dimensions for mouses finding the best ergonomic mouse for large hands is still a tedious task. An ideal mouse should fit in your hand, be gentle on your wrist and shoulder, have a good ergonomic design while offering excellent performance.

Here are a few things which you need to consider before buying a mouse:

  1. Usage (Gaming or Productive activities)
  2. Type of sensor (laser or Optical)
  3. Wired or Wireless
  4. DPI (Dots per inch)
  5. CPI (Count per inch)
  6. Weight and Design
  7. Lighting and Customizations

Considering all these factors, here are our recommendations on what is the best ergonomic wireless mouse that are currently available in the market:


1 Microsoft Sculpt Ergonomic Mouse:

Microsoft Best Ergonomic Mouse For Large Hands

The Microsoft Sculpt Ergonomic Mouse is one of the best-selling ergonomic mice in the market as it is specifically designed to provide optimum comfort even for the users who work for longer hours.

The design of the mice sits naturally on your palm and puts very minimal stress on your wrist, thus ensuring that it provides excellent comfort for varied hand postures. The mouse is slightly tilted to the right, and the thumb scoop will help in maintaining the ergonomic hand and wrist position.

It has got a dedicated windows button through which you can access your windows start menu with a single click right from your mouse. The mouse runs with 2 AA batteries and offers almost 12 months of battery life. The mouse uses a USB dongle to connect, and it has a range of up to 10 feet. It comes with Blue Track technology which helps the mouse to work on most of the surfaces without any problem.

  • Ergonomic design â#8364;“ Easy to usenDedicated windows buttonnLightweightnDecent wireless range
  • Not ideal for large handsnIt uses a USB dongle instead of a BluetoothnIt does not work on clear glass or mirrored surfaces

2 J-Tech Wired Ergonomic mouse:

Vertical Best Ergonomic Mouse For Large Hands

J-tech Digital company based in Houston, Texas, came up with an ergonomic vertical mouse that has a removable palm rest. The mouse is designed in such a way that it can be used in neutral handshake wrist and arm positions, thus providing smoother movement while keeping less stain on wrists.

The mouse comes with a detachable palm rest to ensure optimum comfort to the users, and it also offers features such as adjustable DPI levels of 800,1200,1600, thereby enabling the users to set desired responsiveness of the mouse. It has an optical tracking technology to make sure that the tracking of the movements can be done on a wide range of surfaces.

The functionality of the mouse is also top-notch as it has both back/forward buttons located near the thumb area for optimum convenience. The mouse has an alluring design with blue LED light outlining the mouse. The Size of the mouse is fairly large in terms of dimensions at 5 x 4.5 x 4 inches and weighs only 2 ounces which makes it one of the best ergonomic mice for large hands.

  • Comfortable and attractive designnAdjustable DPI and low latencynLight Weight
  • Average Build QualitynNo RGB lightingnNo programmable buttons

3 Logitech Wireless mouse:

Gaming ergonomic Mouse

The Logitech MX Master 2S Wireless Mouse is one of the best mice for users who are looking for a comfortable all-rounder mouse. With high-quality plastic and a great in-hand feel, the design of the mouse is premium, and the ergonomics are excellent, which ensures that the users do not feel any discomfort while using the mouse for more extended time periods.

The Size of the mouse is also big and heavy, which is a good design feature that makes it the best ergonomic mouse for large hands. The device is compatible with both macOS and Windows and can pair up to 3 devices simultaneously; thus, users can operate three different devices at the same time.

The mouse comes with dual connectivity as it has both a Unifying receiver and Bluetooth Smart wireless technology. Sensor technology (Darkfield high precision). It has got features such as auto-shift scrolling in which speed adaptive scroll wheel auto shifts on the fly. The battery is rechargeable and offers 70 days of battery life on a single charge. Having 7 buttons and the ability to customize them makes it a functional mouse for both productive users and gamers.

  • Sturdy built qualitynComfortable design to holdnCompatibility with not windows and macOSnAdjustable CPI
  • Heavy and BulkynClick latency issuesnNot ideal for small hands

4 Logitech M570 Wireless trackball mouse:

Logitech wheel mouse

In the world of wireless mouses, Logitech has some of the best models out there and talking about the Logitech M570 mouse, it is the earliest wireless mouse that came with a unique ergonomic design and sculpted right-hand shape which provides excellent comfort while not compromising on the performance.

The mouse is compatible with both Windows and macOS and comes with a unifying receiver to connect. The best feature of this mouse is the oversized blue trackball that allows the users to move the cursor on the screen without actually moving the mouse. Although it takes time to get used to this kind of design and functionality after getting hold of its users will enjoy working on it.

The company claims that it can offer a maximum operating distance of 33 feet. The mouse also comes with Logitech Unifying technology, with which the users can connect the mouse to up to 6 wireless devices without the hassle of multiple receivers filling up your USB ports.

  • Unique designnTrackball to move the cursornLong operating distancenLong battery life
  • Not so comfortable for everyonenLack of ability to change DPInNot ideal for gaming

5 Logitech MX Master 3:

Logitech mouse

Logitech MX Master 3 is the best ergonomic mouse for large hands users who are looking for a high-end mouse for casual gaming or general usage. It is a right-handed eight-button mouse with a large thumb wing.

The mouse also comes with 2 click panels, a clickable scroll wheel, and a button below the wheel to change the precision and free-wheeling scroll speeds, and on the side, it has 2 macro buttons, a second scroll wheel, and also a special gesture button on the win which can be used as a function key on keyboard thus providing four additional input options; therefore, it offers high functionality without compromising on the comfort of the user.

The device has got Darkfield sensor, which tracks at up to 4,000 dots per inch (dpi), and it can also track movements on a wide range of surfaces. The battery life on this device is also excellent as it offers a battery life of about 70 days on a single charge. It can connect over Bluetooth or by even using the 2.4GHz unifying adapter, and users can connect up to 3 devices.

  • USB-C chargingnExcellent battery lifenErgonomic designnHighly functional and customizable
  • Only for right-handersnDPI customization isn’t precisenNot ideal for small hands

6 Razer Naga X Wired MMO Gaming mouse:

Razer gaming mouse

For all those hardcore gamers who are looking for a mouse that is specifically designed and developed for gaming, then the Razer Naga X Wired MMO Gaming mouse is one of the best options to go without any hesitation.

The design is sturdy and comfortable to use for long gaming sessions, and the in-hand feel is extremely good because of its ergonomic, and the lightweight nature of the mouse that makes it one of the best ergonomic mouse for large hands. Due to its MMO design, there will an extra support for your non-essential finger, and it also helps to move the mouse without gripping the sides.

Apart from the usual 2 click panels, a scroll wheel, and a DPI cycle button, the main highlight of this mouse has to be its 12 button side pad as a full set which corresponds to the numbers of the keyboard and some additional functions. The Naga X comes with Razer’s 5G Optical Sensor, which tracks at up 18,000 DPI and is accurate at up to 450 inches per second which is more than enough to get an optimum gaming experience. 

  • 12 programable side buttonsnComfortable design for large handsnMade for GamingnExcellent built quality
  • Not compatible with macOSnLack of Bluetooth or wireless featuresnNot suitable for small hands.nLack of tilted scrolling

7 Logitech G604 LIGHTSPEED Wireless gaming mouse:

Logitech gaming mouse for large hand

As we mentioned earlier, Logitech has some of the best mouses in the market, and Logitech G604 LIGHTSPEED is the one which is specifically designed for gaming enthusiasts. The stand-out feature of this is its 15 programmable controls which can be programmed by G hub software.

It has got connectivity with lightspeed wireless and Bluetooth technology that ensures that it operates at ultrafast speed and accuracy. Another key feature of this mouse is its HERO 16K (can be upgraded to 25K) sensor that has precise 1:1 tracking and class-leading power efficiency. The sensors achieve a maximum DPI of 16000-25600 and zero smoothing filtering, thus ensuring that the device has low click latency for gaming activities.

The mouse is well built and has a durable metal scroll wheel that can be switched between hyper-fast and ratcheted scrolling. The mouse can run up to 240 hours in LIGHTSPEED mode or up to 5 months in Bluetooth with a single AA battery. Hence with all these advanced customizable features, Logitech G604 LIGHTSPEED turns to be one of the best ergonomic wireless mouse.

  • Highly customizablenHigh DPI and Low latency speedsnStrong built qualitynLong battery life
  • Not recommended for small hand usersnSlippery base panel

8 Logitech G502 HERO high-performance Wired Gaming mouse:

Best gaming mouse

For all those gaming enthusiasts who are looking for the wired version of the best gaming mouse, which offers both high performance and comfort, the Logitech G502 HERO is the one to get. The Logitech mouses are known for their attractive design, high quality, and Logitech G502 HERO has no exceptions to them.

The design of the mouse is comfortable to hold and has matte black plastic for the primary buttons, grips, and glossy plastic between the mouse’s while is scroll is made up of shiny metal. Logitech G502 features customizable RGB lighting for the DPI indicators and Logitech G logo. The mouse has got a decent heft to it, which helps in keeping the movements smooth and sturdy.

The response time is 1ms, and with the addition of the HERO sensor, the tracking system works flawlessly at 400 inches-per-second and max accelerations over 40Gs. The DPI range is from 100-16000, which is good enough for most intensive gaming activities. Having said that it from all the offerings from Logitech, the G502 HERO is one of the best ergonomic mouse for large hands.

  • Best for GamingnAmple of buttons and customizationsnFlawless sensornComfortable for large hands
  • No option to connect wirelessly nGrips could have been betternUsers might misclick the buttons

9 Logitech G903 LIGHTSPEED Gaming Mouse:


If someone asks what is the best ergonomic wireless mouse, one can commendably say that Logitech G903 LIGHTSPEED Gaming Mouse is the one without hesitation. The G903, the flagship wireless gaming mouse offering from Logitech which provides both high performance and features while not compromising on the build quality and comfort.

The design is sleek and has got a matte finish which can be used by both right and left-handers due to its magnetically secured optional macro buttons. The mouse can store up to five present profiles in its onboard memory and retain up to five different DPI settings and with Logitech’s software customizing them is simple and easy.

The software also calibrates the mouse with the surface of your choice to provide maximum sensor accuracy. The stand-out feature of this mouse is its Powerplay mat which allows a seamless tether between your PC and mouse, providing power and connectivity wirelessly. The G903 has a maximum sensitivity of 12,000 DPI and also offers low click latency compared to its competitors.

  • Unique wireless charging technologynPremium and comfortable design nHighly customizable
  • No RGB lightingnNot so comfortable for left-hand usersnNo Bluetooth connectivity

10 Logitech M510 Wireless Computer mouse:

wireless mouse

For all users looking for a portable and affordable wireless mouse for casual productivity purposes, the Logitech M510 Wireless Computer mouse is the best choice. It is small, compact, and has an ergonomic design for small hands.

The M510 can be comfortably used by both left and right-handers without any discomfort. The mouse comes with a unifying receiver to connect and works on 2 AA batteries that can provide 2 years of battery life. The controls are programmable and can be customized as per user requirements; the mouse weighs only 4.6 ounces which makes it one of the best lightweight, ergonomic mice.

  • Portable nLightweight and sleek designnLong battery life
  • Not ideal for gamingnNot suitable for large handsnNo control over DPI and other customizations

The demand for mouse peripherals is increasing, and more users are looking for mouses that have ergonomic designs and are comfortable to use as per their requirements. The above-mentioned information will answer the questions of what is the best ergonomic wireless mouse and best ergonomic mouse for large hands, thus ensuring that you make the right choice while purchasing your next mouse.

FAQ’s on Best Ergonomic Mouse For Large Hands

 Are ergonomics mouses better than regular standard ones?

Ans Yes, ergonomic mouses are specifically designed to place the users arms in a vertical position, unlike the twisted position in a standard mouse, and this vertical positioning design will reduce the strain on the wrist, shoulder and provides optimum comfort

Are ergonomic mouses good for large hands?

Ans Absolutely, most ergonomic mouses are designed to fit the hands of large sizes without compromising quality and comfort. But it is suggested to check for the dimensions and weight of the mouse before purchasing it to get a rightly fitted mouse.

What is DPI is ergonomic gaming mouses?

Ans: DPI stands for dots per linear inch, and it the measure of mouse sensitivity. By altering the DPI, you can increase or decrease your pointer speed which would help you while gaming or during photo editing. The majority of the new ergonomic mouses come with a high DPI range and the ability to change DPI manually

How to know whether my hand is best suited ergonomic mouse?

Ans: Take a measurement of your hand from the base of your wrist or palm to your middle finger. If the measurement is equal to 17.8cm or more, you can go for large-sized ergonomic mouses; if your hand size less than this, prefer a standard size ergonomic mouse.

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